Research centers and equipment
Interdisciplinary research centers promote cooperation across disciplines and accelerate the translation of basic research results into new treatment methods.
The Translational Research Center (TRC), opened in 2014, features an examplary concept and infrastructure. This research building enables phyisicnas and basic scientists for collaborate closely and develop novel approaches for diagnosing and treating diseases. Currently, experts from the fields of inflammation, tumor, kidney and circulation research work in this building. While some labs are assigned permanently, others are others are made available to rotating clinical research groups.
Core units are centralized technological platforms available to all researchers at the Faculty. Qualified staff support the researchers.
This core unit offers operator-supported cell sorting via a MoFlo-(Beckman Coulter), Astrios (Beckman Coulter) and a FACS AriaII-(Beckton Dickinson) cell-sorter, access to two associated analytical devices (LSR Fortessa and CantoII, Beckton Dickinson) and immunomonitoring services at three locations in Erlangen. It is open to all employees at FAU and Universitätsklinikum Erlangen.
Apart from the core units, researchers can access cost-intensive methods and technologies via the following device platforms.
Genetic and genomic studies for complex traits and clinical studies require high quality DNA-samples of probands as well as a rigorous and reliable handling and tracking of large numbers of samples. Starting in 2009, the IZKF core facility Z4 “DNA-Extraktionsplattform (Biobank)” was established to offer quality controlled DNA-extraction from blood samples and other body fluids, their handling and aliquoting as well as their long-term archiving. The Core Unit has two large scale semi-automatic DNA-extraction platforms, a chemagic magnetic separation module I(Perkin Elmer) and an Autopure LS (Qiagen) and has a capacity of up to 10,000 samples/year. Both platforms yield high quality DNA samples suitable for all downstream applications such as PCR, SNP genotyping, microarray applications and next-generation sequencing. Part of the instrumentation was co-funded by FAU’s Comprehensive Cancer Center. After conclusion of the IZKF funding in 2013 the core facility continues to offer its services financed through user fees.