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BMBF

Collaborative research funded by the German Ministry of Education and Research

Following its application as a “Center of Excellence for Medical Engineering”, Medical Valley EMN was announced on 26 January 2010 as one of five winners in the Leading Edge Cluster Competition sponsored by the BMBF. The decisive, unique selling feature of the Medical Valley EMN Leading Edge Cluster is the common objective among all industrial and academic cluster partners: Interdisciplinary, research-based further development of products, services, and solutions that help to verifiably improve the effectiveness and efficiency of healthcare.

As part of an accompanying evaluation the implementation of the cluster strategy as well as the progress in achieving the stated objectives are reviewed regularly. In total, 45 leading edge cluster projects are making a vital contribution for reaching the objectives. Within ten exemplary selected projects, the respective contribution to increase the efficiency of health care was estimated. In total there is a German wide potential for reduction in health expenditure of more than 1.4 billion Euro per year without diminishing the quality of health care. The products and services developed in these projects are very competitive due to their level of innovation and thus likely to gain market share. The estimated sales potential of some of the products and services is almost 2.9 billion Euro in the period 2015 – 2020. The project ideas have already led to more than 40 granted patents and additional 80 patent applications. Project results were published in over 350 publications.

Contact within the Faculty: Prof. Dr. Dr. h.c. J. Schüttler, Department of Anesthesiology

www.medical-valley-emn.de

Research report Medical Valley

The MIRACUM Consortium (Medical Informatics in Research and Care in University Medicine) was funded for the nine month conceptual phase of the Medical Informatics Funding Scheme of the German Federal Ministry of Research and Education (BMBF; August 2016 to April 2017). Based on its successful pilot projects and its compelling and visionary concept, it will be funded with an amount of 32.1 million Euro for the four-year implementation and networking phase from 2018 onwards.

The aim of the project is to make data from numerous heterogeneous IT systems and databases in patient care and medical research accessible for innovative IT solutions and to support translational research as well as diagnostic and therapeutic decisions in health care processes.

Contact within the Faculty: Prof. Dr. H.-U. Prokosch, Chair of Medical Informatics

www.miracum.org

Research report Miracum

Chronic kidney disease is an increasing health problem, affecting approximately 10% of the population. The burden of morbidity and mortality associated with chronic kidney disease derives from progression to end stage renal disease with requirement of dialysis. Patients suffering from chronic kidney disease have a disproportionate risk of cardiovascular diseases including myocardial infarction and stroke. However, the course of progression of kidney and cardiovascular disease in the setting of renal disease is highly variable and factors determining progression and complication rates are to a large extend unknown.

The number of randomized controlled trials in nephrology lags behind all other medical disciplines. To address these questions, the FAU is coordinating a large prospective observational cohort study in Germany including the cooperation with the universities of Aachen, Berlin, Freiburg, Hannover, Heidelberg, Innsbruck, Jena, München, Regensburg, and Würzburg and a network of approximately 200 nephrologists from different regions all over Germany.

The study aims at gaining important insights on the heterogeneity of disease courses in observing a large number of patients over a long period of time, opening ways for a more deliberate and focused application of existing diagnostic and therapeutic procedures, and developing novel and more effective therapies.

The GCKD Study is funded by the KfH Foundation of Preventive Medicine and the BMBF.

Contact within the Faculty:  Dr. H. Meiselbach, Department of Medicine 4

www.gckd.org

Research report GCKD study

TRENAL („Translational kidney research – from physiology to clinical application“) is an interdisciplinary
network project that aims at leveraging the achievements of basic kidney research and translating them into novel diagnostic and therapeutic strategies. TRENAL unites nephrologists, physiologists, nephropathologists and
basic researchers from FAU, Yale University and University College London (UCL) and the Max Planck Institute for the Science of Light.

TRENAL supports the mobility of students, researchers, physicians in training and professors interested in doing translational kidney research at one of the partner institutions. It furthermore provides financial support for selected conferences and educational events.

Contact within the Faculty: Prof. Dr. M. Goppelt-Strübe, Department of Medicine 4

www.trenal.med.fau.de

Research report TRENAL

METARTHROS is a national collaborative research project investigating the interactions between metabolic and joint diseases.

Contact within the Faculty: Prof. Dr. G. Schett, Prof. Dr. J. Distler, PD Dr. G. Krönke, Dr. S. Finzel, Dr. J. Rech (Department of Medicine 3), Prof. Dr. A. Reis, PD Dr. U. Hüffmeier (Institute of Human Genetics), Prof. Dr. K. Engelke (Institute of Medical Physics)

www.metarthros.de

Research report METARTHROS

How likely do patients develop cancer again after a tumor has been surgically removed? This is the central question of the new research project „MelEVIR – Melanoma, Extracellular Vesicles and Immune Response“ that will be funded by the German Ministry of Education and Research (BMBF) with overall 1.3 million Euro. The project started in April 2016 with a duration of three years.

Contact within the Faculty: Prof. Dr. J. Vera-González, Department of Dermatology

www.melevir.de

Research report MelEVIR